Diseases Treated with Cord Blood

There are a wide range of diseases that are treatable with cord blood, including stem cell disorders, acute and chronic forms of leukemia, myeloproliferative disorders and many more. It’s important to note that, in addition to the host of conditions that can now be treated, it’s the potential of cord blood that holds the most excitement, as research continues to uncover new possibilities.

Diseases That Can Be Treated by Stem Cell Transplantation
Stem Cell Disorders

Aplastic Anemia (Severe)

• Fanconi Anemia

• Paroxysmal Nocturnal Hemoglobinuria (PNH)

• Acute Leukemias

Acute Lymphoblastic Leukemia (ALL)

• Acute Myelogenous Leukemia (AML)

• Acute Biphenotypic Leukemia

• Acute Undifferentiated Leukemia

Chronic Leukemias

• Chronic Myelogenous Leukemia (CML)

• Chronic Lymphocytic Leukemia (CLL)

• Juvenile Chronic Myelogenous Leukemia (JCML)

• Juvenile Myelomonocytic Leukemia (JMML)

Myeloproliferative Disorders

• Acute Myelofibrosis

• Agnogenic Myeloid Metaplasia (myelofibrosis)

• Polycythemia Vera

• Essential Thrombocythemia

Myelodysplastic Syndromes

• Refractory Anemia (RA)

• Refractory Anemia with Ringed Sideroblasts (RARS)

• Refractory Anemia with Excess Blasts (RAEB)

• Refractory Anemia with Excess Blasts in Transformation (RAEB-T)

• Chronic Myelomonocytic Leukemia (CMML)

Lymphoproliferative Disorders

• Non-Hodgkin’s Lymphoma

• Hodgkin’s Disease

• Prolymphocytic Leukemia

Inherited Erythrocyte Abnormalities

• Beta Thalassemia Major

• Pure Red Cell Aplasia

• Sickle Cell Disease

Liposomal Storage Diseases

• Mucopolysaccharidoses (MPS)

• Hurler Syndrome (MPS-IH)

• Scheie Syndrome (MPS-IS)

• Hunter’s Syndrome (MPS-II)

• Sanfilippo Syndrome (MPS-III)

• Morquio Syndrome (MPS-IV)

• Maroteaux-Lamy Syndrome (MPS-VI)

• Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)

• Adrenoleukodystrophy

• Mucolipidosis II (I-cell Disease)

• Krabbe Disease

• Gaucher’s Disease

• Niemann-Pick Disease

• Wolman Disease

• Metachromatic Leukodystrophy

Histiocytic Disorders

• Familial Erythrophagocytic Lymphohistiocytosis

• Histiocytosis-X

• Hemophagocytosis

Phagocyte Disorders

• Chediak-Higashi Syndrome

• Chronic Granulomatous Disease

• Neutrophil Actin Deficiency

• Reticular Dysgenesis

Congenital Immune System Disorders

• Ataxia-Telangiectasia

• Kostmann Syndrome

• Leukocyte Adhesion Deficiency

• DiGeorge Syndrome

• Bare Lymphocyte Syndrome

• Omenn’s Syndrome

• Severe Combined Immunodeficiency (SCID)

• SCID with Adenosine Deaminase Deficiency

• Absence of T & B Cells SCID

• Absence of T Cells, Normal B Cell SCID

• Common Variable Immunodeficiency

• Wiskott-Aldrich Syndrome

• X-Linked Lymphoproliferative Disorder

Inherited Platelet Abnormalities

• Amegakaryocytosis / Congenital Thrombocytopenia

Plasma Cell Disorders

• Multiple Myeloma

• Plasma Cell Leukemia

• Waldenstrom’s Macroglobulinemia

Other Inherited Disorders

• Lesch-Nyhan Syndrome

• Cartilage-Hair Hypoplasia

• Glanzmann Thrombasthenia

• Osteopetrosis

Other Malignancies

• Breast Cancer

• Ewing Sarcoma

• Neuroblastoma

• Renal Cell Carcinoma